Applications of Domino Transformations in Organic Synthesis, by Scott A., Prof. Snyder,Marco Bella,Alexander Dömling,Jon

By Scott A., Prof. Snyder,Marco Bella,Alexander Dömling,Jon Boyce,Gaelle Blond,Iain Coldham

The swift velocity of evolution in domino, or cascade-based differences has revolutionized the perform of chemical synthesis for the construction of common items, designed molecules, and pharmaceuticals.


"Science of Synthesis: functions of Domino variations in natural Synthesis" explores the subject completely and systematically, serving because the foundation for sensible purposes and destiny learn. The 2-volume set provides the state of the art by way of layout, approach, and experimental approaches, resulting in a number of occasions being complete inside of a unmarried response vessel. The content material is prepared via the middle form of response used to start up the development, be it a pericyclic response, a metal-mediated transformation, radical chemistry, or an acid-induced cascade between many others.


Volume 1 covers polyene/cation-pi cyclizations, metathesis, radical, and metal-mediated reactions, and non-radical skeletal rearrangements.

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